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Alzheimer

Experiments by Heidelberg researchers provide insight into novel gene therapy approach to treat Alzheimer's.

“In laboratory experiments on the basic mechanisms that cause Alzheimer's dementia, an international research team led by Heidelberg neurobiologist Prof. Dr. Ulrike Muller and a team of French scientists have succeeded in largely "repairing" the nerve cell damage typical in this disease. The researchers took a closer look at a key protein in Alzheimer's pathogenesis, APP, and one of its cleavage products APPsα. The protein APPsα in turn elicited repair effects and clearly improved memory. The researchers hope to use these findings to explore new approaches in the development of gene therapy for Alzheimer's. Their results were published in the journal Acta Neuropathologica.”

http://www.medicalnewstoday.com/releases/302109.php?tw


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